Journal: Journal of Neuropathology and Experimental Neurology
Article Title: Histological appearance of topical hemostatic agents and materials in neuropathology
doi: 10.1093/jnen/nlaf032
Figure Lengend Snippet: Regular and knit ORC. (A-H) Surgicel Regular. Cellulose fibers in a loosely woven fashion (A, red millimeter paper). The thread is composed of bundles of cellulose fibers (B), that fray when cut. When preserved after processing, ORC fibers are basophilic on microscopy. They are striated along their longitudinal axis, with fraying of the cut ends (C, black arrowheads). The fibers are purple birefringent (D, E). Most often, ORC fibers have dissolved during processing of tissue for microscopy (F, G). The outlines of the fibers and some remnants may be seen, surrounded by fibrin and blood (G). Breakdown of ORC by macrophages may result in groups of macrophages filled with basophilic material (G, white arrowhead). These groups of macrophages may mimic a neoplastic process (H, white arrowheads). (I ) Surgicel Nu-Knit. The more intricately woven Nu-Knit is not readily distinguishable from the regular weave on light microscopy. Scale bar = 100 µm.
Article Snippet: Surgicel Nu-Knit , Ethicon, Johnson & Johnson , ORC , X , .
Techniques: Microscopy, Light Microscopy